Environmental Sciences

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Daniel Schlenk

Professor of Aquatic Ecotoxicology

• Office: 316 Science Laboratories I
• Phone: (951) 827-2018
• daniel.schlenk@ucr.edu

Academic Degrees:

• Ph.D. Oregon State University, 1989
• B.S. Northeast Louisiana University, 1984

Specialization:

• His research focuses on understanding the biochemical factors that influence susceptibility to environmental and natural chemicals. Three specific projects involve the impact of climate change on environmental factors that influence detoxification strategies in aquatic organisms; mechanistic investigations of the effects of salinity on pesticide toxicity in fish; and the role of biotransformation as a mechanism of tolerance to natural and man-made toxic agents.

Research Group:

• Graduate Students

  • Allison Kupsco - Ph.D.
  • Aileen Maldonado - Ph.D., Environmental Sciences
  • Lindley Maryoung -  Ph.D., Environmental Toxicology Graduate Program

• Other

  • Ramon Lavado - Ph.D., Assistant Specialist
  • Jordan Crago - Ph.D., Postdoctoral Research Associate

Representative Publications:

• M.G. Nillos, S. Chajkowski, J. Rimoldi, J. Gan, R. Lavado, D.Schlenk (2010) Stereoselective biotransformation of permethrin to estrogenic metabolites in fish. Chemical Research in Toxicology 23:1568-1575.
• R. Lavado, D.Schlenk (2011) Microsomal biotransformation of chlorpyrifos, parathion and fenthion in rainbow trout (Oncorhynchus mykiss) and coho salmon (Oncorhynchus kisutch): mechanistic insights into interspecific differences in toxicity. Aquatic Toxicology 101: 57-63.
• K. Richardson, D.Schlenk (2011) Biotransformation of 2,2’,5,5’-tetrachlorobiphenyl (PCB 52) and 3,3’,4,4’-tetrachlorobiphenyl (PCB 77) by liver microsomes from four species of sea turtles. Chemical Research in Toxicology 24: 718-725.
• R. Lavado, L. Maryoung, D.Schlenk (2011) Hypersalinity Acclimation Increases the Toxicity of the Insecticide Phorate in Coho Salmon (Oncorhynchus kisutch). Environmental Science and Technology 45: 4623-4629.
• D. Schlenk and R. Lavado (2011) Impacts of climate change on hypersaline conditions of estuaries and xenobiotic toxicity. Aquatic Toxicology 105: S78-S92.
• X. Chen, L. Li , J. Cheng, L. L. Chan, D.-Z. Wang, K.-J.Wang, M. E. Baker, G. Hardiman, D. Schlenk, S. H. Cheng (2011) Molecular staging of marine medaka: A model organism for marine ecotoxicity study. Marine Pollution Bulletin 63: 309-317.
• X. Jiang, X. Li, P. K. S. Lam, S. H. Cheng, D. Schlenk, Y. Sadovy de Mitcheson, Y. Li, J. Gu, L. L. Chan (2011) Proteomic analysis of hepatic tissue of ciguatoxin (CTX) 1 contaminated coral reef fish Cephalopholis argus and moray eel Gymnothorax undulates. Harmful Algae 13:65-71.
• M. L. Brooks, E. Fleishman, L. R. Brown, P. H. Lehman, I. Werner, N. Scholz, C. Mitchelmore, J. R. Lovvorn, M. L. Johnson, D. Schlenk, S. van Drunick, J. I. Drever, D. M. Stoms, A. E. Parker, and R. Dugdale (2012) Life Histories, Salinity Zones, and Sublethal Contributions of Contaminants to Pelagic Fish Declines Illustrated with a Case Study of San Francisco Estuary, California, USA. Estuaries and Coasts 35:603-621.
• R. Lavado, D. Shi, and D. Schlenk (2012) Effects of salinity on the toxicity and biotransformation of l-selenomethionine in Japanese medaka (Oryzias latipes) embryos: Mechanisms of oxidative stress. Aquatic Toxicology 108:18-22.
• N. L. Scholz, E. Fleishman, L. Brown, I. Werner, M. L. Johnson, M. L. Brooks, C. L. Mitchelmore, and D. Schlenk (2012) A perspective on modern pesticides, pelagic fish declines, and unknown ecological resilience in highly managed ecosystems. Bioscience 62:428-434.
• V. Lorenzi, A.C. Mehinto, N. Denslow, and D.Schlenk (2012) Effects of exposure to the B-blocker propranolol on the reproductive behavior and gene expression of the fathead minnow, Pimephales promelas. Aquatic Toxicology 116:8-15.
• D. Bulloch, R. Lavado, K. Forsgren, S. Beni, D. Schlenk, C. Larive, (2012) Analytical and Biological Characterization of Halogenated Gemfibrozil Produced through Wastewater Chlorination. Environmental Science and Technology (in press).
• K. L. Forsgren, X. Deng, G.-H. Lu, S. M. Bay, D. E. Vidal-Dorsch, J. Armstrong, J. R. Gully, D. Schlenk (2012) Annual and seasonal evaluation of reproductive status in hornyhead turbot at municipal wastewater outfalls in the southern California bight. Environmental Toxicology and Chemistry (in press)

Courses Taught:

• ENTX 101 Fundamentals of Toxicology
• ENTX 208/ENSC 208 Ecotoxicology
• ENTX 205 Biotransformation of Organic Chemicals
• ENSC 001 Introduction to Natural Resources
• ENSC 191 Seminar in Professional Development

Graduate Program Affiliations and Research Focus Areas:

• Research Focus Areas

  • Environmental Chemistry and Ecotoxicology

• Programs

  • Environmental Sciences
  • Environmental Toxicology

Honors and Awards

Dr. Schlenk’s honors include his selection as a Fellow of AAAS, as the Chair of USEPA - FIFRA Science Advisory Panel and appointments as a Ray Lankester Fellow at the Marine Biological Association of the United Kingdom, a visiting scholar at the Chinese University of Hong Kong, the Instituto Del Mare in Venice, Italy, the CSIRO Laboratory in Lucas Heights, Australia, and Distinguished Visiting Professor at the State Key Laboratory of Marine Science at Xiamen University, China.

Links:

• Publication List